2-叔丁氧基羰氨基-5-氯苯甲酸 2级

2-叔丁氧基羰氨基-5-氯苯甲酸 2级 - Names and Identifiers

Name	2-[(tert-butoxycarbonyl)amino]-5-chlorobenzoic acid
Synonyms	N-BOC-5-CHLOROANTHRANILIC ACID BOC-2-AMINO-5-CHLOROBENZOIC ACID ANTHRANILIC ACID, N-BOC-5-CHLORO 2-TERT-BUTOXYCARBONYLAMINO-5-CHLORO-BENZOIC ACID 2-Tert-Butoxycarbonylamino-5-chlorolbenzoic acid 2-Tert-Butoxycarbonylamino-5-chloro-benzoic acid 2-tert-Butoxycarbonylamino-5-chloro benzoic acid 2-[(tert-butoxycarbonyl)amino]-5-chlorobenzoic acid 5-Chloro-2-((tert-butoxycarbonyl)amino)benzoic acid 2-[(tert-Butoxycarbonyl)amino]-5-chlorobenzoic acid 5-chloro-2-[[(1,1-dimethylethoxy)carbonyl]amino]-benzoic acid benzoic acid, 5-chloro-2-[[(1,1-dimethylethoxy)carbonyl]amino]-
CAS	253677-29-1
InChI	InChI=1/C12H14ClNO4/c1-12(2,3)18-11(17)14-9-5-4-7(13)6-8(9)10(15)16/h4-6H,1-3H3,(H,14,17)(H,15,16)

2-叔丁氧基羰氨基-5-氯苯甲酸 2级 - Physico-chemical Properties

Molecular Formula	C12H14ClNO4
Molar Mass	271.7
Density	1.338±0.06 g/cm3(Predicted)
Boling Point	350.4±32.0 °C(Predicted)
Flash Point	165.7°C
Vapor Presure	1.65E-05mmHg at 25°C
pKa	3.33±0.36(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.584

2-叔丁氧基羰氨基-5-氯苯甲酸 2级 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	43 - May cause sensitization by skin contact
Safety Description	S24/25 - Avoid contact with skin and eyes. S36/37 - Wear suitable protective clothing and gloves.
Hazard Class	IRRITANT

2-叔丁氧基羰氨基-5-氯苯甲酸 2级 - Introduction

2-[(tert-butoxycarbonyl)amino]-5-chlorobenzoic acid is an organic compound with the chemical formula C12H15ClNO4. The following is a detailed description of its nature, use, preparation and safety information:

Nature:
-Appearance: 2-[(tert-butoxycarbonyl)amino]-5-chlorobenzoic acid is a white crystalline solid.
-Melting point: Its melting point range is 135-137 ° C.
-Solubility: has a certain solubility, soluble in most organic solvents.

Use:
2-[(tert-butoxycarbonyl)amino]-5-chlorobenzoic acid is an important intermediate compound, which is widely used in the field of pharmaceutical synthesis and organic synthesis. It can be used in the preparation of biologically active compounds, such as anti-tumor drugs and anti-viral drugs.

Method:
2-[(tert-butoxycarbonyl)amino]-5-chlorobenzoic acid can be prepared by the following steps:
1.2-amino -5-chlorobenzoic acid and tert-butyl difluoroformate are reacted to generate 2-[(tert-butoxycarbonyl)amino]-5-chlorobenzoic acid ester.
2. The obtained Ester is reacted with a base to remove the ester protecting group to obtain 2-[(tert-butoxycarbonyl)amino]-5-chorobenzoic acid.

Safety Information:
2-[(tert-butoxycarbonyl)amino]-5-chlorobenzoic acid is a relatively safe compound under correct operation and use. But should pay attention to the following matters:
-The compound is a deliquescent substance and should be stored in a dry, sealed container to avoid contact with moisture.
-Wear appropriate protective equipment such as lab gloves, goggles and protective clothing during operation.
-Avoid inhalation of dust, contact with skin, eyes or clothing.
-If accidentally exposed to the compound, flush the affected area with plenty of water and seek medical help.

Please note that the above information is for reference only, and the specific situation still needs to consult relevant information or consult professionals.

Last Update：2024-04-09 15:17:56